Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21940603 | 0.87 | KDM1A (0.43) | GPR119PDK2TSHRALOX15ATM | |
| SCHEMBL21940363 | 0.87 | KDM1A (0.43) | GPR119PDK2TSHRALOX15ATM | |
| SCHEMBL21397495 | 0.79 | ATM (0.41) | GPR119TSHRALOX15ATMKDM1A | |
| SCHEMBL22440518 | 0.79 | ATM (0.41) | GPR119TSHRALOX15ATMKDM1A | |
| SCHEMBL22054837 | 0.79 | ATM (0.41) | GPR119TSHRALOX15ATMKDM1A | |
| SCHEMBL23046236 | 0.79 | IDO1 (0.46) | GPR119TSHRALOX15ATMHDAC1 | |
| SCHEMBL23046109 | 0.79 | KDM4E (0.40) | GPR119TSHRALOX15ATMHDAC1 | |
| SCHEMBL23902047 | 0.79 | ATM (0.41) | GPR119TSHRALOX15ATMKDM1A | |
| SCHEMBL23500668 | 0.79 | IDO1 (0.46) | GPR119TSHRALOX15ATMHDAC1 | |
| SCHEMBL30987345 | 0.79 | IDO1 (0.46) | GPR119TSHRALOX15ATMHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916765-B | Pyridine or pyrimidine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-115916765-A | Pyridine or pyrimidine derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2023-04-04 | — | — | CN | disclosed |