Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104341 | 1.00 | HTR6 (0.39) | HTR6DRD2DRD3HTR1AFGFR4 | |
| SCHEMBL17289979 | 0.92 | PIK3CA (0.39) | NPC1ALDH1A1RAB9AACVR1 | |
| SCHEMBL26103824 | 0.87 | PTGDR2 (0.38) | HTR6ALDH1A1 | |
| SCHEMBL30361980 | 0.87 | PTGDR2 (0.38) | HTR6ALDH1A1 | |
| SCHEMBL4316369 | 0.84 | PTGDR2 (0.34) | ALDH1A1 | |
| SCHEMBL17289752 | 0.82 | HTR6 (0.44) | HTR6DRD2DRD3HTR1AFGFR4 | |
| SCHEMBL4316484 | 0.81 | PTGDR2 (0.34) | HTR6 | |
| SCHEMBL20765228 | 0.81 | HTR6 (0.43) | HTR6NPC1ALDH1A1RAB9A | |
| SCHEMBL2986594 | 0.79 | PTGDR2 (0.42) | HTR6 | |
| SCHEMBL4602394 | 0.78 | PTGDR2 (0.39) | HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076849-A1 | INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR | ORIC PHARMACEUTICALS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |