Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GRM5 | P41594 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904287 | 1.00 | TSHR (0.62) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL20016215 | 0.88 | MEN1 (0.58) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL1968503 | 0.86 | ALOX15 (0.60) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL15903185 | 0.86 | ALOX15 (0.60) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL22243546 | 0.86 | ALOX15 (0.60) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL30643204 | 0.86 | GRM5 (0.62) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL17892572 | 0.83 | CYP1A2 (0.61) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL30643210 | 0.83 | CYP1A2 (0.61) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL3476295 | 0.82 | TSHR (0.67) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| Formic Acid SCHEMBL30595912 | 0.82 | ALOX15 (0.55) | TSHRALOX15CASP1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006035-B1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NEUPHARMA INC (US) | 2023-11-22 | — | — | EP | claimed |
| CN-109843858-B | Certain chemical entities, compositions and methods | 润新生物公司 | 2023-05-05 | — | — | CN | disclosed |