Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | CSF1R | P07333 | 2/20 | 0.55 |
| ▸ | BRAF | P15056 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968503 | 0.86 | ALOX15 (0.60) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| Formic Acid SCHEMBL30595912 | 0.82 | ALOX15 (0.55) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL15904287 | 0.82 | TSHR (0.62) | TSHRMEN1KMT2AALOX15CASP1 | |
| SCHEMBL30362452 | 0.82 | TSHR (0.62) | TSHRMEN1KMT2AALOX15CASP1 | |
| SCHEMBL15903185 | 0.81 | ALOX15 (0.60) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL22243546 | 0.81 | ALOX15 (0.60) | TSHRALOX15CASP1NPSR1HSD17B10 | |
| SCHEMBL30643204 | 0.81 | GRM5 (0.62) | TSHRMEN1KMT2AALOX15CASP1 | |
| SCHEMBL5178391 | 0.80 | MEN1 (1.00) | TSHRMEN1KMT2ARXFP1TRPA1 | |
| SCHEMBL23015752 | 0.80 | RAB9A (0.67) | KMT2AHSD17B10MAPK8MAPK10SMN1; SMN2 | |
| SCHEMBL23410523 | 0.80 | MAPK8 (0.62) | HSD17B10MAPK8MAPK10GRM5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034838-A2 | NEW CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | claimed |