Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.40 |
| ▸ | CHUK | O15111 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30362795 | 0.78 | KDM4C (0.39) | IKBKBCHUKKDM4CTGFBR1TUBB4A | |
| SCHEMBL19949454 | 0.77 | IKBKB (0.39) | IKBKBCHUKKDM4CFYNMAPK8 | |
| SCHEMBL30362954 | 0.76 | KDM4E (0.40) | IKBKBCHUKKDM4CTGFBR1CDC7 | |
| SCHEMBL18076065 | 0.73 | MKNK1 (0.49) | IKBKBCHUKFYNINSRMAPK8 | |
| SCHEMBL19949295 | 0.73 | PLAU (0.48) | IKBKBCHUKTUBB4ATUBBTUBA3C | |
| SCHEMBL28804353 | 0.72 | CDK5 (0.43) | KDM4CTGFBR1L3MBTL1 | |
| SCHEMBL30665045 | 0.72 | CDK5 (0.43) | KDM4CTGFBR1L3MBTL1 | |
| SCHEMBL30363113 | 0.71 | KDM4C (0.42) | IKBKBCHUKKDM4CTGFBR1CDC7 | |
| SCHEMBL21855442 | 0.71 | IKBKB (0.54) | IKBKBKDM4CAPAF1NSD2CASP3 | |
| SCHEMBL14308482 | 0.71 | IKBKB (0.47) | IKBKBPLAUAPAF1NSD2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127080-B | Heterocyclic compounds as kinase inhibitors, compositions comprising the same, and methods of use thereof | 捷思英达医药技术（上海）有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-114127080-B | Heterocyclic compounds as kinase inhibitors, compositions comprising the same, and methods of use thereof | 捷思英达医药技术（上海）有限公司 | 2023-05-05 | — | — | CN | disclosed |