Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929885 | 0.91 | RET (0.51) | RET | |
| Hydrochloric Acid SCHEMBL29615025 | 0.90 | RET (0.50) | RET | |
| Hydrochloric Acid SCHEMBL30363115 | 0.90 | RET (0.50) | RET | |
| SCHEMBL31298400 | 0.80 | RET (0.42) | RET | |
| SCHEMBL15882328 | 0.77 | ROCK2 (0.47) | RET | |
| SCHEMBL30141882 | 0.77 | RET (0.40) | RET | |
| SCHEMBL17324670 | 0.76 | ROCK2 (0.47) | RET | |
| SCHEMBL31298368 | 0.76 | RET (0.38) | RET | |
| SCHEMBL29566683 | 0.75 | RET (0.45) | RET | |
| Hydrochloric Acid SCHEMBL28993707 | 0.74 | RET (0.44) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127080-B | Heterocyclic compounds as kinase inhibitors, compositions comprising the same, and methods of use thereof | 捷思英达医药技术（上海）有限公司 | 2023-05-05 | — | — | CN | disclosed |