SCHEMBL3036362

SCHEMBL3036362

CC[Si](CC)(c1cccc(N)c1)c1cccc(N)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.46
CASP1 P29466 1/20 0.46
RECQL P46063 1/20 0.46
TP53 P04637 1/20 0.44
ESR1 P03372 2/20 0.42
AR P10275 1/20 0.42
ESR2 Q92731 1/20 0.42
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA14 Q9ULX7 1/20 0.38
MAOA P21397 2/20 0.38
MAOB P27338 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29845765 1.00 CYP3A4 (0.46) CYP3A4CASP1RECQLTP53ESR1
SCHEMBL4453580 0.76 CYP3A4 (0.47) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL6422988 0.75 CYP3A4 (0.52) CYP3A4CASP1RECQLTP53ESR1
SCHEMBL30825584 0.75 CYP3A4 (0.52) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL29437105 0.75 CYP3A4 (0.52) CYP3A4CASP1RECQLTP53ESR1
SCHEMBL1172290 0.75 CYP3A4 (0.52) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL3886730 0.74 CYP3A4 (0.58) CYP3A4CASP1RECQLALDH1A1TSHR
SCHEMBL434177 0.74 CYP3A4 (0.48) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL30022263 0.74 CYP3A4 (0.48) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL7132361 0.74 TSHR (0.42) CYP3A4CASP1RECQLTP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240343879-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2024-10-17 US claimed
US-12054598-B2 Polymer aerogel with improved mechanical and thermal properties Blueshift Materials, Inc. (US) 2024-08-06 US claimed
US-20220380568-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2022-12-01 US claimed
US-11427693-B2 Polymer aerogel with improved mechanical and thermal properties BLUESHFT MATERIALS, INC. (US) 2022-08-30 US claimed
EP-3368198-B1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT MAT INC (US) 2022-07-06 EP claimed
CN-108348871-B Highly branched, non-crosslinked aerogels, method for the production thereof and use thereof 蓝移材料有限公司 2021-11-05 CN claimed
US-20200277464-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2020-09-03 US claimed
US-10626239-B2 Polymer aerogel with improved mechanical and thermal properties Blueshift Materials, Inc. (US) 2020-04-21 US claimed
WO-2018200838-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL HAVING MACROPORES, METHODS OF MAKING, AND USES THEREOF Blueshift Materials, Inc. (US) 2018-11-01 WO claimed
US-20180305514-A1 POLYMER AEROGEL WITH IMPROVED MECHANICAL AND THERMAL PROPERTIES Blueshift Materials, Inc. 2018-10-25 US claimed
WO-2012103238-A2 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATIOIN (US) 2012-08-02 WO claimed
US-20120190802-A1 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATION (US) 2012-07-26 US claimed
US-7785517-B2 Methods for reducing or eliminating defects in polymer workpieces NEXOLVE CORPORATION (US) 2010-08-31 US claimed
WO-2009029582-A1 METHODS AND DEVICES FOR REDUCING OR ELIMINATING DEFECTS IN POLYMER WORKPIECES MANTECH SRS TECHNOLOGIES, INC. (US) 2009-03-05 WO claimed
US-20090054615-A1 Methods For Reducing Or Eliminating Defects In Polymer Workpieces BARINGS FINANCE LLC, AS COLLATERAL AGENT 2009-02-26 US claimed
EP-1395627-B1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH DU PONT (US) 2006-11-02 EP claimed
EP-1395627-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-10 EP claimed
US-6653433-B2 From polyamic acids E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-25 US claimed
WO-2002090422-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-11-14 WO claimed
US-20020010311-A1 From polyamic acids E.I. DU PONT DE NEMOURS AND COMPANY 2002-01-24 US claimed