Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30364352

O=C(O)C(F)(F)F.O=C(O)CNCc1ccccc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51
NCOR2 Q9Y618 1/20 0.51
CES1 P23141 1/20 0.47
KEAP1 Q14145 1/20 0.47
DPP7 Q9UHL4 2/20 0.46
FFAR1 O14842 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
ALDH1A1 P00352 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL1191360 0.89 HDAC3 (0.60) HDAC3HDAC1HDAC2NCOR2CES1
SCHEMBL156664 0.89 MEN1 (0.56) HDAC3HDAC1HDAC2NCOR2KEAP1
Ammonia Solution, Strong SCHEMBL27486735 0.87 MEN1 (0.54) HDAC3HDAC1HDAC2NCOR2KEAP1
Hydrochloric Acid SCHEMBL1252387 0.87 MEN1 (0.54) HDAC3HDAC1HDAC2NCOR2KEAP1
Trifluoroacetic Acid SCHEMBL7760565 0.86 SPHK2 (0.56) HDAC3HDAC1HDAC2NCOR2CES1
Trifluoroacetic Acid SCHEMBL28628498 0.83 KEAP1 (0.53) HDAC3HDAC1HDAC2CES1KEAP1
Sulfuric Acid SCHEMBL20299328 0.81 CA2 (0.49) HDAC3HDAC1HDAC2NCOR2ALDH1A1
Trifluoroacetic Acid SCHEMBL27999393 0.81 CES1 (0.53) HDAC3HDAC1HDAC2NCOR2CES1
(Chloromethyl)Benzene SCHEMBL27469312 0.80 MEN1 (0.47) HDAC3HDAC1HDAC2NCOR2KEAP1
SCHEMBL1981483 0.79 MEN1 (0.68) HDAC3HDAC1HDAC2NCOR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119326905-A GalNAc-oligonucleotide conjugate for delivery to liver and preparation method thereof 第一三共株式会社 2025-01-21 CN disclosed
CN-114616332-B GalNAc-oligonucleotide conjugate for delivery to liver and preparation method thereof 第一三共株式会社 2024-09-20 CN disclosed
CN-115976028-A Remedies for glycogen disease type Ia 第一三共株式会社 2023-04-18 CN disclosed