Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30364477 | 0.83 | FGFR1 (0.46) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL30364620 | 0.83 | FGFR1 (0.46) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL11720724 | 0.82 | FGFR1 (0.50) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL25501114 | 0.77 | FGFR1 (0.49) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL30364631 | 0.75 | FGFR1 (0.41) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL9838446 | 0.74 | FGFR1 (0.46) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL19692259 | 0.73 | FGFR1 (0.44) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL17372300 | 0.73 | FGFR1 (0.44) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL29195500 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL27292735 | 0.73 | FGFR1 (0.69) | FGFR1PDE3APDE4DSLC29A1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064223-A1 | TRI-SUBSTITUTED PYRIDINES | GOSSAMER BIO SERVICES, INC. (US) | 2023-04-20 | — | — | WO | disclosed |