Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27200473 | 1.00 | MAPT (0.31) | MAPTDGAT1ATRATRIPCYP17A1 | |
| SCHEMBL27200482 | 0.82 | CYP17A1 (0.35) | MAPTDGAT1ATRATRIPCYP17A1 | |
| SCHEMBL30226522 | 0.79 | CYP17A1 (0.35) | MAPTDGAT1ATRATRIPCYP17A1 | |
| SCHEMBL30413120 | 0.79 | DGAT1 (0.37) | MAPTDGAT1ATRATRIPCYP17A1 | |
| SCHEMBL16793648 | 0.79 | CYP17A1 (0.35) | MAPTDGAT1ATRATRIPCYP17A1 | |
| SCHEMBL25324687 | 0.79 | DGAT1 (0.37) | MAPTDGAT1ATRATRIPCYP17A1 | |
| SCHEMBL25170860 | 0.78 | — | — | |
| SCHEMBL29514122 | 0.77 | MAPT (0.36) | MAPTDGAT1ATRATRIPCYP17A1 | |
| SCHEMBL26720199 | 0.77 | MAPT (0.36) | MAPTDGAT1ATRATRIPCYP17A1 | |
| SCHEMBL29514366 | 0.73 | UCHL1 (0.33) | CYP17A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182323-A1 | PYRIDO OXAZINE AMINO DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-05-24 | — | — | EP | disclosed |
| CN-116075307-A | Pyridooxazine amino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-05 | — | — | CN | disclosed |