Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 14/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986307 | 0.82 | MAPT (0.46) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL31358001 | 0.82 | MAPT (0.46) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL10292640 | 0.81 | S1PR4 (0.56) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL15529186 | 0.80 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL1812248 | 0.80 | S1PR4 (0.52) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL30454502 | 0.79 | S1PR4 (0.51) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL1810729 | 0.79 | S1PR4 (0.51) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL2921634 | 0.78 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL2921638 | 0.78 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 | |
| SCHEMBL18952542 | 0.78 | S1PR4 (0.50) | NPC1RAB9ASMN1; SMN2MAPTS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075307-A | Pyridooxazine amino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-05 | — | — | CN | disclosed |