Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 16/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810729 | 1.00 | S1PR4 (0.51) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1812248 | 0.92 | S1PR4 (0.52) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10292640 | 0.87 | S1PR4 (0.56) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL30365901 | 0.79 | NPC1 (0.49) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2921634 | 0.78 | ALDH1A1 (0.47) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2921638 | 0.78 | ALDH1A1 (0.47) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18952542 | 0.78 | S1PR4 (0.50) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL23851490 | 0.77 | S1PR4 (0.59) | S1PR4NPC1RAB9AMAPTLMNA | |
| SCHEMBL2673898 | 0.77 | NPC1 (0.60) | S1PR4NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18952588 | 0.77 | S1PR4 (0.49) | S1PR4NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |