Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462598 | 0.88 | GPR119 (0.58) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL6132848 | 0.84 | GPR119 (0.69) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL1673519 | 0.84 | GPR119 (0.63) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL5272983 | 0.83 | GPR119 (0.55) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL5573222 | 0.83 | MAPT (0.76) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL12676600 | 0.82 | MAPT (0.58) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL19212239 | 0.81 | MAPT (0.57) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL7381177 | 0.81 | SMN1; SMN2 (0.56) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL23331678 | 0.80 | GPR119 (0.53) | GPR119MAPTALDH1A1LMNANAMPT | |
| SCHEMBL24120522 | 0.80 | GPR119 (0.54) | GPR119MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676922-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | Astrazeneca AB (SE) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024189488-A1 | BIFUNCTIONAL COMPOUNDS CAPABLE OF DEGRADING ANDROGEN RECEPTORS | ASTRAZENECA AB (SE) | 2024-09-19 | — | — | WO | disclosed |
| EP-4405051-A1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023046806-A1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-03-30 | — | — | WO | disclosed |