Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843148 | 0.88 | NAMPT (0.66) | GPR119MAPTLMNANAMPTTP53 | |
| SCHEMBL5462598 | 0.86 | GPR119 (0.58) | GPR119MAPTLMNAALDH1A1NAMPT | |
| SCHEMBL31198857 | 0.86 | GPR119 (0.57) | GPR119MAPTLMNAALDH1A1NAMPT | |
| Acetic Acid SCHEMBL29880486 | 0.85 | NAMPT (0.63) | GPR119MAPTLMNANAMPTTP53 | |
| SCHEMBL1458887 | 0.85 | GPR119 (0.76) | GPR119MAPTLMNAALDH1A1NAMPT | |
| SCHEMBL1673519 | 0.85 | GPR119 (0.63) | GPR119MAPTLMNAALDH1A1NAMPT | |
| Dimethylamine SCHEMBL6608623 | 0.84 | NAMPT (0.65) | GPR119MAPTLMNANAMPTTP53 | |
| SCHEMBL30366165 | 0.84 | GPR119 (0.56) | GPR119MAPTLMNAALDH1A1NAMPT | |
| SCHEMBL5573222 | 0.84 | MAPT (0.76) | GPR119MAPTLMNAALDH1A1NAMPT | |
| SCHEMBL5542227 | 0.83 | GPR119 (0.65) | GPR119MAPTLMNAALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |