Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | SCN1A | P35498 | 3/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432679 | 0.82 | ALDH1A1 (0.50) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL31741261 | 0.82 | ALDH1A1 (0.50) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL16999006 | 0.82 | TSHR (0.55) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL30499383 | 0.80 | CYP2C19 (0.43) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL31295913 | 0.79 | CYP2C19 (0.49) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL27751215 | 0.79 | CYP2C19 (0.49) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL11877321 | 0.79 | CYP2C19 (0.44) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL22610224 | 0.77 | CYP2C19 (0.47) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL4938951 | 0.76 | CYP2C19 (0.46) | TSHRCYP2C19LMNAALDH1A1CYP3A4 | |
| SCHEMBL13747766 | 0.76 | TSHR (0.46) | TSHRCYP2C19LMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075307-A | Pyridooxazine amino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-05 | — | — | CN | disclosed |