Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375935 | 0.78 | HTR3A (0.56) | HTR3A | |
| Hydrochloric Acid SCHEMBL21385247 | 0.76 | P2RY14 (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL18633599 | 0.76 | HTR3A (0.58) | HTR3A | |
| SCHEMBL23073892 | 0.74 | — | — | |
| SCHEMBL2885151 | 0.74 | HTR3A (0.46) | HTR3A | |
| SCHEMBL30899636 | 0.74 | CHRNB2 (0.40) | HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL941521 | 0.72 | NPC1 (0.47) | HTR3A | |
| SCHEMBL23062573 | 0.71 | MAPT (0.58) | — | |
| Hydrochloric Acid SCHEMBL4892700 | 0.70 | HTR2C (0.47) | HTR3AHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4892694 | 0.70 | HTR2C (0.47) | HTR3AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405051-A1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2024-07-31 | — | — | EP | disclosed |
| CN-118076604-A | Pyrazolo [3,4-b ] pyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2024-05-24 | — | — | CN | disclosed |
| WO-2023046806-A1 | PYRAZOLO[3,4-B]PYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2023-03-30 | — | — | WO | disclosed |