Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26079034 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL26079035 | 0.85 | PIK3CA (0.49) | ALDH1A1KDM4EHPGDMAPTGAA | |
| Lithium Ion SCHEMBL30366548 | 0.83 | PIK3CA (0.41) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL1180546 | 0.79 | PIK3CA (0.47) | MAPK1SMN1; SMN2PIK3CAMTORPIK3CD | |
| SCHEMBL26071916 | 0.79 | KDM4E (0.41) | ALDH1A1KDM4EMAPTTSHRGLA | |
| SCHEMBL30366515 | 0.79 | KDM4E (0.41) | ALDH1A1KDM4EMAPTTSHRGLA | |
| SCHEMBL19849051 | 0.77 | SMN1; SMN2 (0.41) | ALDH1A1KDM4EMAPK1SMN1; SMN2PIK3CA | |
| SCHEMBL1181308 | 0.75 | SMN1; SMN2 (0.40) | KDM4EMAPTMAPK1SMN1; SMN2PIK3CA | |
| SCHEMBL29788273 | 0.75 | PIK3CA (0.40) | ALDH1A1MAPK1SMN1; SMN2PIK3CAMTOR | |
| SCHEMBL190265 | 0.75 | PIK3CA (0.40) | ALDH1A1MAPK1SMN1; SMN2PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165045-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | Monash University (AU) | 2023-04-19 | — | — | EP | disclosed |