Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26079080 | 0.89 | GAA (0.47) | GAAPIK3CAKDM4ENPC1RAB9A | |
| SCHEMBL30366376 | 0.83 | KMO (0.46) | PIK3CAKDM4ENPC1RAB9APOLB | |
| SCHEMBL26071660 | 0.78 | GAA (0.54) | GAAKDM4ENPC1RAB9ARXFP1 | |
| SCHEMBL30366650 | 0.77 | GAA (0.53) | GAAKDM4ENPC1RAB9ARXFP1 | |
| SCHEMBL16277642 | 0.75 | TP53 (0.48) | GAAPIK3CAKDM4ERXFP1POLB | |
| SCHEMBL19736708 | 0.73 | KDM4E (0.54) | GAAPIK3CAKDM4ENPC1RAB9A | |
| SCHEMBL16283454 | 0.72 | TP53 (0.49) | GAAPIK3CAKDM4ERXFP1POLB | |
| SCHEMBL26072211 | 0.72 | PIK3CA (0.44) | GAAPIK3CAKDM4ERXFP1POLB | |
| SCHEMBL17594976 | 0.72 | PIK3CA (0.54) | GAAPIK3CAKDM4EPOLBKMT2A | |
| SCHEMBL24378546 | 0.72 | DPP4 (0.45) | GAAPIK3CAKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165045-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | Monash University (AU) | 2023-04-19 | — | — | EP | disclosed |