Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366406 | 0.83 | GAA (0.46) | POLBPIK3CAHPGDLMNAHSD17B10 | |
| SCHEMBL26079080 | 0.70 | GAA (0.47) | POLBPIK3CAHPGDLMNAHSD17B10 | |
| SCHEMBL21054975 | 0.69 | MAPT (0.57) | HPGDLMNAKDM4EMAPTALDH1A1 | |
| SCHEMBL21135207 | 0.69 | ATR (0.41) | ATRPOLBPIK3CAHPGDLMNA | |
| SCHEMBL26072359 | 0.68 | PIK3CA (0.50) | KMOPOLBPIK3CAPIK3R1PIK3CD | |
| SCHEMBL21135206 | 0.67 | ATR (0.38) | ATRPOLBPIK3CAHPGDLMNA | |
| SCHEMBL21033175 | 0.67 | KDM4E (0.54) | KMOPOLBPKMLMNAKDM4E | |
| SCHEMBL26072768 | 0.67 | RXFP1 (0.56) | KMOPOLBPIK3CAPKMCFTR | |
| SCHEMBL16950261 | 0.67 | KMO (0.55) | KMOPOLBPIK3CAPKMLMNA | |
| SCHEMBL21135204 | 0.66 | PIK3CB (0.39) | ATRPOLBPIK3CALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165045-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | Monash University (AU) | 2023-04-19 | — | — | EP | disclosed |