⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576607 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27665874 | 0.98 | HSP90AA1 (0.41) | — | |
| SCHEMBL27411725 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL27571277 | 0.98 | — | — | |
| Bromide SCHEMBL27776140 | 0.98 | — | — | |
| Methylamine SCHEMBL2702693 | 0.93 | HSP90AA1 (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL28489431 | 0.83 | L3MBTL1 (0.37) | — | |
| SCHEMBL11865773 | 0.83 | P2RX7 (0.42) | — | |
| SCHEMBL2818091 | 0.75 | — | — | |
| SCHEMBL14160121 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 981 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-B | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-117466942-A | Chiral secondary phosphine oxide compound, chiral quinazolinone/pyrimidinone ring derivative based on chiral secondary phosphine oxide compound and application of chiral quinazolinone/pyrimidinone ring derivative | 中山大学 | 2024-01-30 | — | — | CN | claimed |
| CN-116457355-A | 2-amino-3-carbonyl imidazopyridines and pyrazolopyridines compounds | 第一生物治疗股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-114764064-A | Gold magnetic-mediated fluorescence chemical nasal sensor for rapidly typing pathogenic microorganisms | 海南大学 | 2022-07-19 | — | — | CN | claimed |
| CN-113214282-B | AChE/BACE1/GSK3 beta three-target inhibitor, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2022-03-22 | — | — | CN | claimed |
| CN-113214282-A | AChE/BACE1/GSK3 beta three-target inhibitor, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2021-08-06 | — | — | CN | claimed |
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-108003154-B | Method for synthesizing paliperidone intermediate by using microchannel reactor | 黑龙江鑫创生物科技开发有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-107188898-B | Process for preparing thienopyrimidine compounds | 霍夫曼-拉罗奇有限公司 | 2019-12-03 | — | — | CN | claimed |
| CN-106459092-B | Compounds for the treatment of spinal muscular atrophy | 豪夫迈·罗氏有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-1247586-C | Substituted 2-pyrimidinyl-6, 7,8, 9-tetrahydropyrimido [1, 2-A ] pyrimidin-4-one and 7-pyrimidinyl-2, 3-dihydroimidazo [1, 2-A ] pyrimidin-5 (1H) one derivatives for the treatment of neurodegenerative diseases | SANOFI AVENTIS SYNTHELABO (FR) | 2006-03-29 | — | — | CN | claimed |
| EP-1620381-A1 | HYDROANTHRACENE BASED COMPOUNDS AS ANTICANCER AGENTS | Dabur Research Foundation (IN) | 2006-02-01 | — | — | EP | claimed |
| CN-1714083-A | Novel pyrimidine-4,6-dicarboxamides for the selective inhibition of collagenases | AVENTIS PHARMA GMBH (DE) | 2005-12-28 | — | — | CN | claimed |
| US-6949557-B2 | Hydroanthracene based compounds as anticancer agents | DABUR RESEARCH FOUNDATION (IN) | 2005-09-27 | — | — | US | claimed |
| CN-1556810-A | Substituted 2-pyrimidinyl-6, 7,8, 9-tetrahydropyrimido [1, 2-A ] pyrimidin-4-one and 7-pyrimidinyl-2, 3-dihydroimidazo [1, 2-A ] pyrimidin-5 (1H) one derivatives for the treatment of neurodegenerative diseases | ����ɳŵ��-����������˾ | 2004-12-22 | — | — | CN | claimed |
| WO-2004096742-A1 | HYDROANTHRACENE BASED COMPOUNDS AS ANTICANCER AGENTS | DABUR RESEARCH FOUNDATION (IN) | 2004-11-11 | — | — | WO | claimed |
| US-20040220197-A1 | Hydroanthracene based compounds as anticancer agents | DABUR RESEARCH FOUNDATION | 2004-11-04 | — | — | US | claimed |
| CN-1449398-A | 2-pyridyl-6, 7,8, 9-tetrahydropyrimido [1, 2-a ] pyrimidin-4-one and 7-pyridyl-2, 3-dihydroimidazo [1, 2-a ] pyrimidin-5 (1H) one derivatives | SANOFI SYNTHELABO (FR) | 2003-10-15 | — | — | CN | claimed |
| CN-1049430-C | Sulfonamide compound, preparation method and application thereof | HOFFMANN LA ROCHE (CH) | 2000-02-16 | — | — | CN | claimed |
| CN-1095375-A | Novel sulfonamides | HOFFMANN LA ROCHE (CH) | 1994-11-23 | — | — | CN | claimed |