Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725932 | 0.82 | KDM4E (0.41) | MAPTABL1BCRPIK3CAMAPK1 | |
| SCHEMBL21630876 | 0.78 | RAPGEF4 (0.33) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL31038514 | 0.76 | HPGD (0.35) | KMT2AMEN1MAPK1HPGD | |
| SCHEMBL30507693 | 0.73 | SMN1; SMN2 (0.38) | L3MBTL1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL3199564 | 0.71 | RAPGEF4 (0.38) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL27225358 | 0.69 | RAPGEF4 (0.36) | L3MBTL1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL28628697 | 0.68 | RAPGEF4 (0.35) | L3MBTL1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL28587275 | 0.66 | F2 (0.35) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL23852054 | 0.66 | RAPGEF4 (0.33) | MAPTMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL21630533 | 0.65 | RAPGEF4 (0.39) | L3MBTL1PIK3CAKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165045-A1 | DUAL KINASE-BROMODOMAIN INHIBITORS | Monash University (AU) | 2023-04-19 | — | — | EP | disclosed |