Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 15/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366524 | 0.83 | MAPK1 (0.46) | MTORALOX5APFEN1PIK3CA | |
| SCHEMBL30367019 | 0.70 | ALOX5AP (0.48) | ALOX5APFEN1 | |
| SCHEMBL30366958 | 0.70 | ALOX5AP (0.43) | MTORALOX5APFEN1PIK3CA | |
| SCHEMBL31275471 | 0.66 | MAPK1 (0.47) | — | |
| SCHEMBL7875295 | 0.64 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL19243723 | 0.64 | MKNK1 (0.59) | MTORPIK3CA | |
| SCHEMBL31264760 | 0.64 | EIF2AK3 (0.50) | — | |
| SCHEMBL31264739 | 0.64 | EIF2AK3 (0.49) | — | |
| SCHEMBL4724651 | 0.63 | CPS1 (0.56) | — | |
| SCHEMBL7876966 | 0.63 | MTOR (1.00) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894481-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |