Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 9/20 | 0.43 |
| ▸ | FEN1 | P39748 | 9/20 | 0.43 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HCK | P08631 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367019 | 0.86 | ALOX5AP (0.48) | ALOX5APFEN1EIF2AK3GRM2AAK1 | |
| SCHEMBL30366806 | 0.86 | TEK (0.43) | EIF2AK3RIPK1RETKDRSRC | |
| SCHEMBL30366837 | 0.78 | ALOX5AP (0.36) | ALOX5APFEN1EIF2AK3RETKDR | |
| SCHEMBL31213920 | 0.74 | FGFR1 (0.49) | EGFRBTK | |
| SCHEMBL28981098 | 0.73 | ALOX5AP (0.38) | ALOX5APFEN1GRM2 | |
| SCHEMBL30717994 | 0.71 | TRPA1 (0.45) | ALOX5APFEN1 | |
| SCHEMBL30717977 | 0.71 | TRPA1 (0.45) | ALOX5APFEN1 | |
| SCHEMBL31264744 | 0.71 | EIF2AK3 (0.47) | EIF2AK3RIPK1 | |
| SCHEMBL30366844 | 0.70 | MTOR (0.47) | ALOX5APFEN1PIK3CAMTOR | |
| SCHEMBL30366769 | 0.70 | KDR (0.35) | RETKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894481-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |