Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 14/20 | 0.48 |
| ▸ | FEN1 | P39748 | 12/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366958 | 0.86 | ALOX5AP (0.43) | ALOX5APFEN1GRM2AAK1EIF2AK3 | |
| SCHEMBL30367018 | 0.84 | CYP3A4 (0.46) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31361288 | 0.81 | ALOX5AP (0.47) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL26106772 | 0.80 | CYP3A4 (0.56) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL29407664 | 0.80 | CYP3A4 (0.56) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31361279 | 0.80 | ALOX5AP (0.47) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31264646 | 0.80 | EIF2AK3 (0.46) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL28981128 | 0.75 | ALOX5AP (0.54) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31213925 | 0.75 | FGFR4 (0.60) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 | |
| SCHEMBL31213850 | 0.75 | FGFR1 (0.73) | ALOX5APFEN1CYP3A4CYP2D6FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894481-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |