Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 9/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2626785 | 0.98 | TERT (0.44) | TERTAPPAPAF1KDM1AEGFR | |
| SCHEMBL12312493 | 0.98 | TERT (0.44) | TERTAPPAPAF1KDM1AEGFR | |
| Hydrochloric Acid SCHEMBL30898816 | 0.97 | TERT (0.43) | TERTAPPAPAF1KDM1AEGFR | |
| Hydrochloric Acid SCHEMBL41927 | 0.97 | TERT (0.43) | TERTAPPAPAF1KDM1AEGFR | |
| Methylene Blue Cation SCHEMBL30367710 | 0.87 | APP (0.55) | TERTAPPAPAF1KDM1AEGFR | |
| Iodide SCHEMBL30367691 | 0.87 | EGFR (0.44) | APPAPAF1KDM1AEGFRMEN1 | |
| Methylene Blue Cation SCHEMBL1207285 | 0.87 | APP (0.55) | TERTAPPAPAF1KDM1AEGFR | |
| SCHEMBL2626789 | 0.85 | EGFR (0.46) | APPAPAF1KDM1AEGFRMEN1 | |
| Methylene Blue Cation SCHEMBL12312498 | 0.85 | APP (0.57) | TERTAPPAPAF1KDM1AEGFR | |
| Methylene Blue Cation SCHEMBL12312491 | 0.85 | APP (0.57) | TERTAPPAPAF1KDM1AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410155-A | Method for preparing 3, 7-bis (dimethylamino) phenothiazin-5-ium iodide | 普如制药生命解决方案公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-110382472-B | Method for preparing 3, 7-bis (dimethylamino) phenothiazin-5-ium iodide | 普如制药生命解决方案公司 | 2023-05-09 | — | — | CN | disclosed |