Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | QDPR | P09417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30289618 | 0.78 | TNK2 (0.48) | NAMPTALDH1A1TNK2 | |
| SCHEMBL30289687 | 0.78 | TNK2 (0.48) | NAMPTALDH1A1TNK2 | |
| SCHEMBL30289735 | 0.74 | BTK (0.45) | — | |
| SCHEMBL30289785 | 0.73 | BTK (0.46) | — | |
| SCHEMBL30289664 | 0.71 | TNK2 (0.48) | ALDH1A1TNK2 | |
| SCHEMBL30289622 | 0.71 | TNK2 (0.65) | NAMPTTNK2GRM1GRM5ATR | |
| SCHEMBL30289688 | 0.71 | CDK9 (0.40) | TNK2GRIA1 | |
| SCHEMBL30289733 | 0.70 | TNK2 (0.46) | NAMPTALDH1A1TNK2 | |
| SCHEMBL30367672 | 0.69 | NAMPT (0.38) | NAMPTALDH1A1LMNASLC2A1MAPT | |
| SCHEMBL30367634 | 0.69 | MAPT (0.41) | ALDH1A1LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |