Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367576 | 0.75 | ROCK1 (0.62) | MAPTLMNARAB9AALDH1A1RXFP1 | |
| SCHEMBL30289663 | 0.74 | TNK2 (0.44) | RAB9AROCK1NPC1 | |
| SCHEMBL30499529 | 0.74 | KMT2A (0.43) | MAPTLMNARAB9AALDH1A1PIK3CA | |
| SCHEMBL30289660 | 0.73 | SCN9A (0.40) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30499520 | 0.69 | MAPT (0.44) | MAPTLMNAALDH1A1PKMROCK1 | |
| SCHEMBL30289747 | 0.69 | TNK2 (0.41) | ALDH1A1ROCK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30289605 | 0.69 | TNK2 (0.41) | MAPTALDH1A1KDM4E | |
| SCHEMBL4526945 | 0.64 | ROCK1 (0.57) | MAPTLMNARAB9AALDH1A1PIK3CA | |
| SCHEMBL27636023 | 0.62 | MAPT (0.61) | MAPTLMNARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5390679 | 0.61 | MAPT (0.47) | MAPTLMNAALDH1A1ROCK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |