Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCND2 | P30279 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22923843 | 0.92 | MEN1 (0.49) | MEN1KMT2ASLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL22924008 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL22923842 | 0.81 | LMNA (0.45) | MEN1KMT2AKCNH2LMNADRD2 | |
| SCHEMBL30367378 | 0.78 | MEN1 (0.55) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22923865 | 0.76 | MEN1 (0.53) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22923929 | 0.76 | DRD2 (0.45) | MEN1KMT2ALMNAHTR6DRD2 | |
| SCHEMBL22924015 | 0.74 | MEN1 (0.35) | MEN1KMT2AKCNH2ALDH1A1LMNA | |
| SCHEMBL22923862 | 0.73 | MEN1 (0.56) | MEN1KMT2ASLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL22923944 | 0.71 | MEN1 (0.50) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL22923868 | 0.71 | MEN1 (0.48) | MEN1KMT2AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012717-A1 | ANTITUMOR COMPOUND USED AS AXL INHIBITOR AND USE THEREOF | 南京华威医药科技集团有限公司 | 2021-01-28 | — | — | WO | disclosed |