Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | BLK | P51451 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367672 | 0.83 | NAMPT (0.38) | NAMPTLMNAALDH1A1IKBKBHRH4 | |
| SCHEMBL30585433 | 0.81 | ALDH1A1 (0.46) | LMNAALDH1A1HRH4SLC2A1HTT | |
| SCHEMBL30585444 | 0.77 | HRH4 (0.37) | LMNAALDH1A1IKBKBHRH4CSF1R | |
| SCHEMBL30367031 | 0.75 | NAMPT (0.43) | NAMPTCSF1RKITBLK | |
| SCHEMBL12973252 | 0.73 | MAPT (0.45) | LMNAIKBKBHRH4CSF1RKIT | |
| SCHEMBL30585421 | 0.73 | HRH4 (0.47) | LMNAALDH1A1IKBKBHRH4HTT | |
| SCHEMBL2818604 | 0.73 | IKBKB (0.44) | LMNAALDH1A1IKBKBHRH4CSF1R | |
| SCHEMBL30367366 | 0.72 | HTT (0.41) | LMNAIKBKBHRH4CSF1RKIT | |
| SCHEMBL30367315 | 0.71 | NAMPT (0.45) | NAMPTLMNAALDH1A1IKBKBMAPT | |
| SCHEMBL30367527 | 0.70 | MERTK (0.38) | LMNAALDH1A1CSF1RKITBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |