Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818604 | 0.87 | IKBKB (0.44) | HTTIKBKBMEN1KMT2ACYP1A2 | |
| SCHEMBL12973252 | 0.85 | MAPT (0.45) | HTTIKBKBMEN1KMT2ACYP1A2 | |
| SCHEMBL2818684 | 0.79 | RAB9A (0.50) | HTTMEN1KMT2AARSMN1; SMN2 | |
| SCHEMBL30585421 | 0.76 | HRH4 (0.47) | HTTIKBKBMEN1KMT2ALMNA | |
| SCHEMBL30585460 | 0.76 | HRH4 (0.45) | IKBKBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL30585459 | 0.75 | HRH4 (0.41) | IKBKBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL30585433 | 0.74 | ALDH1A1 (0.46) | HTTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL13041794 | 0.74 | KIT (0.49) | MEN1KMT2ALMNASMN1; SMN2CSF1R | |
| SCHEMBL14366552 | 0.74 | CSF1R (0.39) | HTTIKBKBLMNACSF1RKIT | |
| SCHEMBL30585444 | 0.72 | HRH4 (0.37) | HTTIKBKBMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |