Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367634 | 0.69 | MAPT (0.41) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL2831148 | 0.69 | ALDH1A1 (0.64) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL28417525 | 0.67 | MAPT (0.51) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL24096640 | 0.67 | RET (0.40) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL30367576 | 0.67 | ROCK1 (0.62) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL18447788 | 0.64 | MAPT (0.54) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL18447787 | 0.64 | KMT2A (0.55) | MAPTLMNAMEN1KMT2AIDO1 | |
| SCHEMBL27636023 | 0.64 | MAPT (0.61) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL5390679 | 0.64 | MAPT (0.47) | MAPTLMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL4526945 | 0.64 | ROCK1 (0.57) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |