Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367634 | 0.74 | MAPT (0.41) | KMT2AMEN1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL14880488 | 0.70 | KCNJ1 (0.63) | KMT2AMEN1LMNAHTTCRHBP | |
| SCHEMBL1304880 | 0.68 | MAPT (0.52) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30366987 | 0.67 | KMT2A (0.53) | KMT2AMEN1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL30367508 | 0.67 | LMNA (0.42) | KMT2AMEN1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL3974325 | 0.66 | APP (0.74) | KMT2AMEN1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL2455303 | 0.66 | APP (0.74) | KMT2AMEN1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL18449581 | 0.65 | APP (0.60) | KMT2AMEN1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL10019306 | 0.65 | MAPT (0.50) | KMT2AMEN1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL30367576 | 0.65 | ROCK1 (0.62) | KMT2AMEN1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |