Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23887755 | 1.00 | MAOB (0.39) | MAOBHPGDGAAMAPTMAOA | |
| SCHEMBL25551414 | 1.00 | MAOB (0.39) | MAOBHPGDGAAMAPTMAOA | |
| SCHEMBL30367739 | 0.86 | MAOB (0.41) | MAOBHPGDMAOAALDH1A1RAB9A | |
| SCHEMBL23887742 | 0.86 | MAOB (0.41) | MAOBHPGDMAOAALDH1A1RAB9A | |
| SCHEMBL23886863 | 0.78 | MAOB (0.44) | MAOBHPGDMAOAALDH1A1RAB9A | |
| SCHEMBL23896349 | 0.78 | RAB9A (0.38) | HPGDGAAMAPTALDH1A1RAB9A | |
| SCHEMBL25195489 | 0.78 | RAB9A (0.38) | HPGDGAAMAPTALDH1A1RAB9A | |
| SCHEMBL25545023 | 0.78 | RAB9A (0.39) | HPGDGAAMAPTALDH1A1RAB9A | |
| SCHEMBL23887737 | 0.78 | RAB9A (0.39) | HPGDGAAMAPTALDH1A1RAB9A | |
| SCHEMBL30120995 | 0.77 | HPGD (0.33) | HPGDGAAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697969-A | 7-or 8-hydroxy-isoquinoline and 7-or 8-hydroxy-quinoline derivatives as alpha-1 antitrypsin modulators for the treatment of alpha-1 antitrypsin deficiency (AATD) | 弗特克斯药品有限公司 | 2023-02-03 | — | — | CN | disclosed |