Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DNTT | P04053 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483872 | 0.72 | NFKB1 (0.32) | — | |
| SCHEMBL6924804 | 0.70 | GSK3A (0.41) | TSHRKMT2AALDH1A1LMNAHSD17B10 | |
| SCHEMBL27499179 | 0.69 | NFKB1 (0.44) | KMT2AALDH1A1MAPTHPGDDNTT | |
| SCHEMBL9334938 | 0.68 | MIF (0.32) | TSHRKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL27579908 | 0.67 | TSHR (0.39) | TSHRKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL27582041 | 0.67 | TSHR (0.39) | TSHRKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7929530 | 0.66 | DNTT (0.37) | TSHRALDH1A1HSD17B10POLBDNTT | |
| SCHEMBL9755515 | 0.66 | DNTT (0.41) | ALDH1A1L3MBTL1DNTTCYP1A2 | |
| SCHEMBL10360118 | 0.65 | TSHR (0.36) | TSHRKMT2AALDH1A1LMNAMAPT | |
| SCHEMBL9495622 | 0.65 | PTGER2 (0.44) | TSHRALDH1A1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096705-A | Novel compounds | NRG治疗有限公司 | 2023-05-09 | — | — | CN | disclosed |