SCHEMBL7929530

SCHEMBL7929530

COC(=O)C1C=CC=CC1=O

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DNTT P04053 2/20 0.37
ALDH1A1 P00352 1/20 0.35
POLB P06746 2/20 0.33
POLA1 P09884 1/20 0.33
MMP2 P08253 1/20 0.31
ANPEP P15144 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
BRD4 O60885 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28776161 0.81 NFKB1 (0.39) NFKB1NFKB2RELAMAPK1
SCHEMBL30569223 0.79 GABRR1 (0.30)
SCHEMBL27367444 0.79 NFKB1 (0.38) ALDH1A1POLBNFKB1NFKB2RELA
SCHEMBL27548114 0.79 TSHR (0.31) MMP2TSHR
SCHEMBL28234221 0.78 DNTT (0.33) DNTTALDH1A1
SCHEMBL27443733 0.78 ALDH1A1 (0.31) DNTTALDH1A1
SCHEMBL28818565 0.77 ALDH1A1 (0.30) ALDH1A1
SCHEMBL27369224 0.77 ALDH1A1 (0.36) DNTTALDH1A1NFKB1NFKB2RELA
SCHEMBL8814334 0.76
SCHEMBL4554819 0.76 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5773034-A Cutaneous rejuvenating and healing product, method for its manufacture and uses thereof FORTUNE BASE MANAGEMENT, LTD. (HK) 1998-06-30 US claimed
CN-115715292-A 1H-pyrazolo [4,3-g ] isoquinoline and 1H-pyrazolo [4,3-g ] quinoline derivatives as alpha-1-antitrypsin modulators for the treatment of alpha-1-antitrypsin deficiency (AATD) 弗特克斯药品有限公司 2023-02-24 CN disclosed
CN-113423427-A IRAK degrading agents and uses thereof 凯麦拉医疗公司 2021-09-21 CN disclosed
CN-112218859-A Modulators of proteolysis and related methods of use 阿尔维纳斯运营股份有限公司 2021-01-12 CN disclosed
CN-108135788-B Method for producing coating film 花王株式会社 2019-06-21 CN disclosed
CN-108135789-B Method for producing coating film 花王株式会社 2019-05-21 CN disclosed
CN-106501535-B A kind of kit of the compound releasing agent of ANS salt and detection Blood cortisol 迪瑞医疗科技股份有限公司 2018-11-09 CN disclosed
CN-108135788-A Method for producing coating film 花王株式会社 2018-06-08 CN disclosed
CN-108135789-A METHOD FOR PRODUCING COATING FILM 花王株式会社 2018-06-08 CN disclosed
CN-107918013-A The method and kit of K Ras albumen in chemiluminescence Enzyme immunoassay circulating tumor cell 浙江天科高新技术发展有限公司 2018-04-17 CN disclosed
EP-0707486-B1 CUTANEOUS REJUVENATING AND HEALING PRODUCT, METHOD FOR ITS MANUFACTURE AND USES THEREOF FORTUNE BASE MAN LTD (HK) 2001-08-08 EP disclosed
CN-1186487-A Acetamide derivatives, process for producing the same, and medicinal composition containing the same DAINIPPON PHARMACEUTICAL CO (JP) 1998-07-01 CN disclosed
US-5773034-A Cutaneous rejuvenating and healing product, method for its manufacture and uses thereof FORTUNE BASE MANAGEMENT, LTD. (HK) 1998-06-30 US disclosed
US-5773034-A Cutaneous rejuvenating and healing product, method for its manufacture and uses thereof FORTUNE BASE MANAGEMENT, LTD. (HK) 1998-06-30 US disclosed
CN-1184470-A Thienyl-, Furyl-, Pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORP (US) 1998-06-10 CN disclosed
EP-0707486-A1 CUTANEOUS REJUVENATING AND HEALING PRODUCT, METHOD FOR ITS MANUFACTURE AND USES THEREOF PEARL VENTURES, Inc. (US) 1996-04-24 EP disclosed
WO-1995030426-A1 CUTANEOUS REJUVENATING AND HEALING PRODUCT, METHOD FOR ITS MANUFACTURE AND USES THEREOF CAMPRASSE SERGE (FR) 1995-11-16 WO disclosed
CN-1036687-A TRIAZINE HERBICIDES SHELL INT RESEARCH (NL) 1989-11-01 CN disclosed
CN-87104230-A Different  oxazolidinone derivative and production method thereof 1987-12-23 CN disclosed
CN-86102923-A The method for preparing antibiotic derivatives 1986-11-12 CN disclosed