Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | CPT2 | P23786 | 2/20 | 0.34 |
| ▸ | CPT1A | P50416 | 2/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 7/20 | 0.33 |
| ▸ | GUCY1A2 | P33402 | 7/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 7/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301766 | 0.84 | TRAP1 (0.37) | KDM4EHSP90B1TRAP1ALDH1A1FFAR1 | |
| SCHEMBL30301748 | 0.84 | TRAP1 (0.35) | LMNAHPGDHSP90B1TRAP1AGTR2 | |
| SCHEMBL30970485 | 0.83 | HSP90AA1 (0.33) | KDM4ELMNAHPGDHTTHSP90B1 | |
| SCHEMBL30970486 | 0.83 | HSP90AA1 (0.33) | KDM4ELMNAHPGDHTTHSP90B1 | |
| SCHEMBL30368511 | 0.83 | TRAP1 (0.34) | PTGER1HSP90B1TRAP1 | |
| SCHEMBL30301546 | 0.82 | TRAP1 (0.39) | PDE4DPDE4APDE4BPDE4CCPT2 | |
| SCHEMBL30301782 | 0.82 | PDE4D (0.34) | PDE4DPDE4APDE4BPDE4CCPT2 | |
| SCHEMBL30156753 | 0.78 | PTGER1 (0.36) | PDE4DPDE4APDE4BPDE4CCPT2 | |
| SCHEMBL24913820 | 0.76 | HSP90B1 (0.39) | PDE4DPDE4APDE4BPDE4CCPT2 | |
| SCHEMBL30789164 | 0.76 | HSP90B1 (0.39) | PDE4DPDE4APDE4BPDE4CCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996907-A | Inhibitors of MLH1 and/or PMS2 for cancer treatment | 奈奥芬莱有限公司 | 2023-04-21 | — | — | CN | disclosed |