Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 5/20 | 0.71 |
| ▸ | CDK8 | P49336 | 3/20 | 0.71 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29004618 | 1.00 | AXL (0.71) | AXLCDK8KITCDK2CCNT1 | |
| SCHEMBL13356904 | 0.85 | CDK8 (0.63) | AXLCDK8CDK2CCNT1CCNA2 | |
| SCHEMBL13745366 | 0.84 | CDK8 (0.77) | AXLCDK8KITCDK2CCNT1 | |
| SCHEMBL13745464 | 0.83 | CDK8 (1.00) | AXLCDK8KITCDK2CCNT1 | |
| SCHEMBL8320115 | 0.83 | CDK8 (0.84) | AXLCDK8KITCDK2CCNT1 | |
| SCHEMBL17939499 | 0.83 | AXL (0.76) | AXLCDK8KITTNIKNTRK1 | |
| SCHEMBL13745368 | 0.83 | CDK8 (0.76) | AXLCDK8KITCDK2CCNT1 | |
| SCHEMBL8313308 | 0.83 | CDK8 (0.76) | AXLCDK8KITCDK2CCNT1 | |
| SCHEMBL1516669 | 0.83 | CDK8 (0.76) | AXLCDK8KITCDK2CCNT1 | |
| SCHEMBL30368724 | 0.83 | AXL (0.76) | AXLCDK8KITTNIKNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991705-B | 3- (1H pyrrolo [2,3-b ] pyridin-5-yl) benzoyl derivatives, preparation and application thereof | 安徽医科大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-115991705-A | 3- (1H pyrrolo [2,3-b ] pyridin-5-yl) benzoyl derivatives, preparation and application thereof | 安徽医科大学 | 2023-04-21 | — | — | CN | disclosed |