Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.57 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547818 | 1.00 | MGLL (0.61) | MGLLNR1H3SCN2AMEN1KMT2A | |
| SCHEMBL29841157 | 1.00 | MGLL (0.61) | MGLLNR1H3SCN2AMEN1KMT2A | |
| SCHEMBL725608 | 0.86 | NR1H3 (0.67) | MGLLNR1H3SCN2AMEN1KMT2A | |
| SCHEMBL19317166 | 0.84 | MEN1 (0.52) | NR1H3SCN2AMEN1KMT2AESR1 | |
| SCHEMBL9453237 | 0.83 | KDM4E (0.52) | MGLLMEN1KMT2AESR1ESR2 | |
| SCHEMBL9453234 | 0.83 | MGLL (0.51) | MGLLNR1H3SCN2AMEN1KMT2A | |
| SCHEMBL8588168 | 0.80 | ESR1 (0.54) | NR1H3SCN2AMEN1KMT2AGRM5 | |
| SCHEMBL29644720 | 0.80 | MGLL (0.56) | MGLLNR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL29644719 | 0.80 | MGLL (0.56) | MGLLNR1H3MEN1KMT2ANR1H2 | |
| SCHEMBL19707567 | 0.80 | MGLL (0.66) | MGLLMEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996755-A | Bifunctional molecules and methods of use thereof | 旗舰创业创新VI有限责任公司 | 2023-04-21 | — | — | CN | disclosed |