SCHEMBL725608

SCHEMBL725608

O=C1c2ccccc2C(=O)N1c1cccc(N2C(=O)c3ccccc3C2=O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 2/20 0.67
SCN2A Q99250 3/20 0.65
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
GRM5 P41594 1/20 0.59
ESR1 P03372 2/20 0.58
HTT P42858 1/20 0.57
NR1H2 P55055 1/20 0.56
HSPA1A P0DMV8 1/20 0.55
PABPC1 P11940 1/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
ALDH1A1 P00352 1/20 0.54
GAA P10253 1/20 0.54
FAAH O00519 1/20 0.54
MGLL Q99685 1/20 0.54
PIM3 Q86V86 1/20 0.53
HIPK4 Q8NE63 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2553055 0.87 KDM4E (0.68) NR1H3SCN2AMEN1KMT2AGRM5
SCHEMBL8474317 0.87 NR1H3 (0.64) NR1H3SCN2AMEN1KMT2AGRM5
SCHEMBL11618620 0.86 NR1H3 (0.57) NR1H3SCN2AMEN1KMT2AGRM5
SCHEMBL13460685 0.86 NR1H3 (0.67) NR1H3SCN2AMEN1KMT2AGRM5
SCHEMBL7400864 0.86 PGR (0.63) NR1H3SCN2AMEN1KMT2AGRM5
SCHEMBL259386 0.86 MEN1 (0.67) NR1H3SCN2AMEN1KMT2AHTT
SCHEMBL13910988 0.86 KMT2A (0.67) NR1H3SCN2AMEN1KMT2AGRM5
SCHEMBL1662738 0.86 ESR1 (0.80) NR1H3SCN2AMEN1KMT2AGRM5
SCHEMBL7547818 0.86 MGLL (0.61) NR1H3SCN2AMEN1KMT2AGRM5
SCHEMBL29841157 0.86 MGLL (0.61) NR1H3SCN2AMEN1KMT2AGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2582755-B1 TRANSPARENT POLYIMIDE-POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-04-06 EP claimed
US-8546516-B2 Transparent polyimide-polyester compositions, method of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-10-01 US claimed
EP-2582755-A1 TRANSPARENT POLYIMIDE-POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2013-04-24 EP claimed
WO-2011159827-A1 TRANSPARENT POLYIMIDE-POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-22 WO claimed
US-20110303577-A1 TRANSPARENT POLYIMIDE-POLYESTER COMPOSITIONS, METHOD OF MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2011-12-15 US claimed
EP-3562859-B1 METHODS FOR THE MANUFACTURE OF POLYETHERIMIDES AND POLYETHERIMIDES MADE BY THE METHOD SABIC GLOBAL TECHNOLOGIES BV (NL) 2021-07-28 EP disclosed
EP-3245243-B1 POLYETHERIMIDE MISCIBLE POLYMER BLENDS FOR CAPACITOR FILMS SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-12-09 EP disclosed
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS THE SCRIPPS RESEARCH INSTITUTE 2020-10-08 US disclosed
US-10669388-B2 Polyetherimide miscible polymer blends for capacitor films SABIC GLOBAL TECHNOLOGIES, B.V. (NL) 2020-06-02 US disclosed
US-10640613-B2 Thermoplastic polyimides, method for the manufacture thereof, and articles prepared therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-05-05 US disclosed
EP-2771384-B1 POLYETHERIMIDES, METHODS OF MANUFACTURE, AND ARTICLES FORMED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-03-20 EP disclosed
US-20190040201-A1 THERMOPLASTIC POLYIMIDES, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-02-07 US disclosed
US-20080161576-A1 METHOD OF FORMING A DRY QUATERNARY AMMONIUM SALT MIXTURE GENERAL ELECTRIC COMPANY (US) 2008-07-03 US disclosed
US-7291696-B2 Composition and associated method GENERAL ELECTRIC COMPANY (US) 2007-11-06 US disclosed
US-20070106052-A1 Composition and associated method GENERAL ELECTRIC COMPANY (US) 2007-05-10 US disclosed
US-20070106052-A1 Composition and associated method GENERAL ELECTRIC COMPANY (US) 2007-05-10 US disclosed
US-20070102349-A1 Membrane and associated method GENERAL ELECTRIC COMPANY (US) 2007-05-10 US disclosed
US-20070102349-A1 Membrane and associated method GENERAL ELECTRIC COMPANY (US) 2007-05-10 US disclosed
EP-1783147-A1 Composition and associated method GENERAL ELECTRIC COMPANY (US) 2007-05-09 EP disclosed
EP-1782881-A1 Membrane and associated method General Electric Company (US) 2007-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS ALDH1A2, DDT, CLTB NR1H3 608/4885SCN2A 4281/4885MEN1 2493/4885
US-20080161576-A1 METHOD OF FORMING A DRY QUATERNARY AMMONIUM SALT MIXTURE AGT, CA2, CA3 NR1H3 3812/4885SCN2A 252/4885MEN1 2978/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.