Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 13/20 | 0.71 |
| ▸ | CDK5R1 | Q15078 | 13/20 | 0.71 |
| ▸ | GSK3B | P49841 | 11/20 | 0.71 |
| ▸ | CDK2 | P24941 | 6/20 | 0.71 |
| ▸ | CCNB2 | O95067 | 6/20 | 0.71 |
| ▸ | CDK1 | P06493 | 6/20 | 0.71 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.71 |
| ▸ | PRKACA | P17612 | 6/20 | 0.71 |
| ▸ | PRKACG | P22612 | 6/20 | 0.71 |
| ▸ | PRKACB | P22694 | 6/20 | 0.71 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.71 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.71 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.71 |
| ▸ | CDK9 | P50750 | 5/20 | 0.71 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.71 |
| ▸ | CLK1 | P49759 | 5/20 | 0.71 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.71 |
| ▸ | HTR2B | P41595 | 2/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28982776 | 1.00 | CDK5 (0.71) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| Meridianin A SCHEMBL29354190 | 0.83 | CDK5 (1.00) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| SCHEMBL28982781 | 0.83 | CDK5 (0.71) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| Meridianin A SCHEMBL28982793 | 0.83 | CDK5 (1.00) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| SCHEMBL30369303 | 0.83 | CDK5 (0.71) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| SCHEMBL30369347 | 0.80 | HTR1A (1.00) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| SCHEMBL28982783 | 0.80 | HTR1A (1.00) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| SCHEMBL2239702 | 0.80 | CDK5 (1.00) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| SCHEMBL28982791 | 0.78 | DYRK1A (1.00) | CDK5CDK5R1GSK3BCDK2CCNB2 | |
| SCHEMBL30369497 | 0.78 | DYRK1A (1.00) | CDK5CDK5R1GSK3BCDK2CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925686-B | MERIDIANIN derivatives, lewis acid-promoted coupling synthesis method and application thereof | 贵州医科大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-115925686-A | Meridianin derivatives, coupling synthesis method and application thereof promoted by Lewis acid | 贵州医科大学 | 2023-04-07 | — | — | CN | disclosed |