⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27780233 | 0.98 | — | — | |
| Carbamic Acid SCHEMBL27921000 | 0.92 | NPC1 (0.43) | — | |
| SCHEMBL28222175 | 0.92 | PDE4A (0.37) | — | |
| Pyridine SCHEMBL28823602 | 0.88 | KMT2A (0.36) | — | |
| SCHEMBL18190 | 0.80 | NPC1 (0.42) | — | |
| Quinoline SCHEMBL27521930 | 0.80 | ALDH1A1 (0.52) | — | |
| SCHEMBL1973074 | 0.78 | — | — | |
| SCHEMBL4765851 | 0.78 | — | — | |
| SCHEMBL6420210 | 0.76 | — | — | |
| SCHEMBL10834562 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294757-A | A kind of copper catalysis one kettle way prepares the synthetic method and application of C-3 thiocarbamoyl imidazoles and pyridine derivatives | 青岛科技大学 | 2019-10-01 | — | — | CN | claimed |
| CN-106061481-B | The combination of androgen receptor inhibitor and AKT inhibitor for treating cancer | 诺华股份有限公司 | 2019-08-16 | — | — | CN | claimed |
| CN-107383028-B | The miscellaneous thiocarbamoyl imidazole compound of 1,2,3,4- tetrahydro-beta-carboline-N- and preparation and application | 浙江大学 | 2019-03-08 | — | — | CN | claimed |
| CN-109369538-A | N-difluoromethyl azole thiourea (selenium) derivative and preparation method thereof | 华南农业大学 | 2019-02-22 | — | — | CN | claimed |
| CN-108997319-A | Thiocarbamoyl imidazole alkanone derivative and its synthetic method and application | 江苏师范大学 | 2018-12-14 | — | — | CN | claimed |
| CN-108727270-A | A kind of preparation method of 2- thiocarbamoyl imidazoles alkane -4,5- diketone | 南京信息工程大学 | 2018-11-02 | — | — | CN | claimed |
| CN-107383028-A | The miscellaneous thiocarbamoyl imidazole compounds of 1,2,3,4 tetrahydro-beta-carboline N and preparation and application | 浙江大学 | 2017-11-24 | — | — | CN | claimed |
| CN-105218540-B | A kind of preparation method of 3 thiocarbamoyl imidazoles of C simultaneously [1,2 a] pyridine compounds and their | 曲阜师范大学 | 2017-07-04 | — | — | CN | claimed |
| CN-104746081-B | Functionalization imidazole ion liquid corrosion inhibiter and its preparation method and application | 中国科学院兰州化学物理研究所 | 2017-03-29 | — | — | CN | claimed |
| CN-105593222-A | Compounds for affinity chromatography and for extending the half-life of therapeutic agents | GLAXOSMITHKLINE IP DEV LTD | 2016-05-18 | — | — | CN | claimed |
| CN-1414994-A | Polymer dispersion with cross-linking resin, method for producing the same and use thereof | HENKEL KGAA (DE) | 2003-04-30 | — | — | CN | claimed |
| EP-0906311-B1 | N-SULFONYLIMIDAZOLES USED AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2003-04-23 | — | — | EP | claimed |
| US-20010029237-A1 | Annulated azole derivatives useful as microbicidal agents | ASSMANN LUTZ (DE) | 2001-10-11 | — | — | US | claimed |
| CN-1249752-A | Fused azole derivatives for use as microbicides | BAYER AG (DE) | 2000-04-05 | — | — | CN | claimed |
| US-6043377-A | MICROBICIDES USEFUL IN CROP PROTECTION AND IN THE PROTECTION OF MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-28 | — | — | US | claimed |
| EP-0966467-A1 | ANNULATED AZOLE DERIVATIVES USEFUL AS MICROBICIDAL AGENTS | Bayer Aktiengesellschaft (DE) | 1999-12-29 | — | — | EP | claimed |
| CN-1227551-A | N-sulfonylimidazoles used as fungicides | BAYER AG (DE) | 1999-09-01 | — | — | CN | claimed |
| EP-0906311-A1 | N-SULFONYLIMIDAZOLES USED AS FUNGICIDES | BAYER AG (DE) | 1999-04-07 | — | — | EP | claimed |
| WO-1998039331-A1 | ANNULATED AZOLE DERIVATIVES USEFUL AS MICROBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-11 | — | — | WO | claimed |
| WO-1997047620-A1 | N-SULFONYLIMIDAZOLES USED AS FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-18 | — | — | WO | claimed |