SCHEMBL30371663

SCHEMBL30371663

O=C1c2ccccc2C(=O)N1CCCc1ccccc1

nearest known ligand 0.86

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.86
L3MBTL1 Q9Y468 1/20 0.86
CASP3 P42574 1/20 0.69
ALDH1A1 P00352 2/20 0.68
ALDH2 P05091 1/20 0.68
PKM P14618 1/20 0.68
ALDH3A1 P30838 1/20 0.68
TSHR P16473 1/20 0.65
MAPK1 P28482 1/20 0.65
GSK3A P49840 1/20 0.65
GSK3B P49841 1/20 0.65
CYP1B1 Q16678 1/20 0.64
KDM4E B2RXH2 1/20 0.60
GAA P10253 1/20 0.60
MAPT P10636 1/20 0.60
RAB9A P51151 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
ACHE P22303 2/20 0.59
MAOB P27338 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45050 1.00 TDP1 (0.86) TDP1L3MBTL1CASP3ALDH1A1ALDH2
SCHEMBL916601 0.94 TDP1 (0.96) TDP1L3MBTL1CASP3ALDH1A1ALDH2
SCHEMBL13442856 0.93 CASP3 (0.81) TDP1L3MBTL1CASP3ALDH1A1ALDH2
SCHEMBL29263641 0.93 TDP1 (1.00) TDP1L3MBTL1CASP3GSK3AGSK3B
SCHEMBL31035964 0.93 TDP1 (1.00) TDP1L3MBTL1CASP3GSK3AGSK3B
SCHEMBL8434811 0.93 TDP1 (1.00) TDP1L3MBTL1CASP3GSK3AGSK3B
SCHEMBL9219707 0.93 TDP1 (1.00) TDP1L3MBTL1CASP3GSK3AGSK3B
SCHEMBL5093425 0.93 TDP1 (1.00) TDP1L3MBTL1CASP3GSK3AGSK3B
SCHEMBL29724090 0.88 CASP3 (0.86) TDP1L3MBTL1CASP3ALDH1A1ALDH2
SCHEMBL1142116 0.88 CASP3 (0.86) TDP1L3MBTL1CASP3ALDH1A1ALDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111566116-B Novel metal complex, process for producing the same, and process for producing gamma-lactam compound using the same 基础科学研究院 2023-06-09 CN disclosed