Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16055663 | 1.00 | RIPK1 (0.39) | RIPK1CES2CES1GAAALDH1A1 | |
| SCHEMBL16067539 | 1.00 | RIPK1 (0.39) | RIPK1CES2CES1GAAALDH1A1 | |
| SCHEMBL16055660 | 1.00 | RIPK1 (0.39) | RIPK1CES2CES1GAAALDH1A1 | |
| SCHEMBL16055661 | 1.00 | RIPK1 (0.39) | RIPK1CES2CES1GAAALDH1A1 | |
| SCHEMBL17458648 | 1.00 | RIPK1 (0.39) | RIPK1CES2CES1GAAALDH1A1 | |
| SCHEMBL15051104 | 0.86 | CES2 (0.45) | CES2CES1ALDH1A1LMNACYP3A4 | |
| SCHEMBL252963 | 0.86 | CYP1A2 (0.39) | ALDH1A1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19415506 | 0.86 | CYP1A2 (0.39) | ALDH1A1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20604426 | 0.86 | CYP1A2 (0.39) | ALDH1A1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20604401 | 0.86 | CYP1A2 (0.39) | ALDH1A1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |