Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 4/20 | 0.67 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034555 | 0.81 | KCNA3 (1.00) | KCNA3KCNN4KMT2AMEN1MAPT | |
| SCHEMBL3038159 | 0.80 | KCNA3 (0.78) | KCNA3KCNN4KMT2AMEN1MAPT | |
| SCHEMBL3045470 | 0.78 | KCNA3 (0.75) | KCNA3KCNN4KMT2AMEN1MAPT | |
| SCHEMBL3041480 | 0.78 | KCNA3 (1.00) | KCNA3KCNN4KMT2AMEN1MAPT | |
| SCHEMBL28665779 | 0.75 | KCNA3 (0.89) | KCNA3KCNN4MAPTALDH1A1LMNA | |
| SCHEMBL3041693 | 0.75 | KCNA3 (0.70) | KCNA3KCNN4MAPTALDH1A1POLB | |
| SCHEMBL8667382 | 0.74 | KCNA3 (0.68) | KCNA3KCNN4KMT2AMEN1MAPT | |
| SCHEMBL14601696 | 0.73 | KMT2A (1.00) | KMT2AMEN1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3038345 | 0.70 | KCNA3 (1.00) | KCNA3KCNN4KMT2AMEN1MAPT | |
| SCHEMBL3039239 | 0.69 | KCNA3 (0.61) | KCNA3KCNN4MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216772-A1 | Novel Phenantridine Analogues and Uses Thereof | 4SC AG (DE) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216772-A1 | Novel Phenantridine Analogues and Uses Thereof | P2RX4, P2RX5, CLIC4 | KCNA3 52/4885KCNN4 50/4885KMT2A 2236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.