SCHEMBL30375343

SCHEMBL30375343

S=C1NCc2cncnc2N1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MB P02144 1/20 0.33
MKNK2 Q9HBH9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1270310 0.78 MB (0.56) MBMKNK2
SCHEMBL29547390 0.78 MB (0.56) MBMKNK2
SCHEMBL13801620 0.72 ADRA2A (0.38) MB
SCHEMBL17396612 0.70 MKNK2 (0.35) MBMKNK2
SCHEMBL18013213 0.69 ASIC3 (0.31)
SCHEMBL30967258 0.68
SCHEMBL2992191 0.68
SCHEMBL30172972 0.68 ASIC3 (0.40)
Bromide SCHEMBL6507677 0.68 ASIC3 (0.30)
SCHEMBL30033667 0.67 MKNK2 (0.30) MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116253735-B Pyrimidopyrimidinone compounds and uses thereof 江苏开元药业有限公司 2025-05-02 CN disclosed
WO-2024041634-A1 TRICYCLIC COMPOUND AND USE THEREOF 先声再明医药有限公司 2024-02-29 WO disclosed
CN-116253735-A Pyrimidopyrimidinone compounds and uses thereof 江苏开元药业有限公司 2023-06-13 CN disclosed