Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CCR3 | P51677 | 4/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24069429 | 0.93 | SLC6A2 (0.63) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL24070124 | 0.92 | MEN1 (0.60) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL25758331 | 0.90 | MEN1 (0.58) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL25290527 | 0.90 | SLC6A2 (0.59) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL25758537 | 0.89 | HTR7 (0.58) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL29022584 | 0.89 | SMN1; SMN2 (0.57) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL25758335 | 0.89 | HTR7 (0.62) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL25758526 | 0.89 | CCR3 (0.58) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL25758544 | 0.89 | MEN1 (0.69) | HTR7MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL25289791 | 0.88 | HTR7 (0.73) | HTR7MEN1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4159718-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |