SCHEMBL25758537

SCHEMBL25758537

O=S(=O)(NCCCN1CCC(Cc2ccccc2)CC1)c1ccc(-c2ccc(Cl)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 2/20 0.58
SLC6A2 P23975 8/20 0.58
SLC6A4 P31645 7/20 0.58
SLC6A3 Q01959 3/20 0.58
KMT2A Q03164 2/20 0.57
HTT P42858 2/20 0.57
MEN1 O00255 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CCR1 P32246 2/20 0.55
ALDH1A1 P00352 2/20 0.54
TP53 P04637 1/20 0.54
GAA P10253 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24069429 0.94 SLC6A2 (0.63) HTR7SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL25290527 0.90 SLC6A2 (0.59) HTR7SLC6A2SLC6A4KMT2AHTT
SCHEMBL25758526 0.90 CCR3 (0.58) HTR7SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL25758544 0.90 MEN1 (0.69) HTR7SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL30376178 0.89 HTR7 (0.69) HTR7SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL25759699 0.87 HTR7 (0.59) HTR7SLC6A2SLC6A4KMT2AHTT
SCHEMBL25758458 0.87 SLC6A2 (0.61) SLC6A2SLC6A4SLC6A3KMT2AHTT
SCHEMBL24070124 0.86 MEN1 (0.60) HTR7SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL25758331 0.84 MEN1 (0.58) HTR7SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL29022584 0.83 SMN1; SMN2 (0.57) HTR7SLC6A2SLC6A4SLC6A3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 US disclosed
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 US disclosed
EP-4159718-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS Daegu-Gyeongbuk Medical Innovation Foundation (KR) 2023-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS SLC6A2, SLC6A3, SLC6A4 HTR7 79/4885SLC6A2 1/4885SLC6A4 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.