Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ASPH | Q12797 | 2/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.46 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.46 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26767103 | 0.91 | GAA (0.49) | GAAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28788200 | 0.87 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL6379087 | 0.86 | MEN1 (0.49) | MAPTMEN1KMT2AL3MBTL1NPC1 | |
| SCHEMBL937116 | 0.85 | MEN1 (0.54) | GAAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28788196 | 0.84 | HDAC3 (0.46) | MAPTNPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL29396220 | 0.83 | HDAC3 (0.45) | GAAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL29071950 | 0.82 | MEN1 (0.48) | GAAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3078231 | 0.78 | MEN1 (0.54) | GAAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL31283173 | 0.76 | KDM4E (0.44) | GAAMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL27711221 | 0.76 | MEN1 (0.51) | GAAMAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210880-B1 | Benzoxazinone derivatives | MSD KK (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-8314094-B2 | Benzoxazinone derivative | MSD K.K (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20100210636-A1 | BENZOXAZINONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. | 2010-08-19 | — | — | US | disclosed |
| EP-2210880-A1 | BENZOXAZINONE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210636-A1 | BENZOXAZINONE DERIVATIVE | HAX1, CYP4X1, CYP19A1 | GAA 1992/4885MAPT 4320/4885MEN1 1370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.