Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 15/20 | 0.84 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.84 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.84 |
| ▸ | MMP2 | P08253 | 1/20 | 0.84 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.84 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 13/20 | 0.53 |
| ▸ | OSBP | P22059 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23742688 | 1.00 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL11036838 | 1.00 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL11036550 | 1.00 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL29574915 | 1.00 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL23742687 | 1.00 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL1229229 | 0.92 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL2138507 | 0.92 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL7128580 | 0.92 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL26422779 | 0.89 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL26422803 | 0.89 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230129745-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS TO TREAT METABOLIC DISEASE | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230129745-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS TO TREAT METABOLIC DISEASE | ASAH1, ACACB, ACACA | AKR1C3 326/4885AKR1B10 525/4885AKR1B1 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.