Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 14/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 1.00 |
| ▸ | MMP2 | P08253 | 1/20 | 1.00 |
| ▸ | PAK1 | Q13153 | 1/20 | 1.00 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | STAT3 | P40763 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 12/20 | 0.60 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Artepillin SCHEMBL1229229 | 1.00 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL7128580 | 1.00 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL25890163 | 0.95 | AKR1C3 (0.91) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL26422962 | 0.95 | AKR1C3 (0.91) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL8467360 | 0.92 | AKR1C3 (0.86) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL8467358 | 0.92 | AKR1C3 (0.86) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL23742688 | 0.92 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL11036838 | 0.92 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL29574915 | 0.92 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL30378377 | 0.92 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10314918-B2 | Jasmonate derivatives and compositions thereof | NANOCARE TECHNOLOGIES, INC. (US) | 2019-06-11 | — | — | US | claimed |
| US-20060110520-A1 | Active oxygen eliminator derived from natural substance and use thereof | MIDORIKAWA KIYOSHI | 2006-05-25 | — | — | US | claimed |
| EP-1621194-A1 | ACTIVE OXYGEN ELIMINATOR ORIGINATING IN NATURAL MATERIAL AND USE OF THE SAME | Nihon Propolis Co., Ltd. (JP) | 2006-02-01 | — | — | EP | claimed |
| EP-1575689-A2 | TYPING NATURAL PRODUCTS | Marcucci Ribeiro, Maria Cristina (BR) | 2005-09-21 | — | — | EP | claimed |
| US-20040126437-A1 | Typing natural products | RIBEIRO MARIA CRISTINA MARCUCC (BR) | 2004-07-01 | — | — | US | claimed |
| US-20030065229-A1 | Phenol derivatives, process for preparation of the same and use thereof | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2003-04-03 | — | — | US | claimed |
| WO-2002051516-A2 | TYPING NATURAL PRODUCTS | MARCUCCI RIBEIRO MARIA CRISTIN (BR) | 2002-07-04 | — | — | WO | claimed |
| EP-1184362-A1 | PHENOL DERIVATIVES, PROCESS FOR PREPARATION OF THE SAME AND USE THEREOF | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2002-03-06 | — | — | EP | claimed |
| US-5830914-A | 3-(4-HYDROXY-3,5-BIS(3-METHYL-2-BUTENYL)PHENYL)ACRYLIC ACID AND SALTS | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1998-11-03 | — | — | US | claimed |
| EP-0867187-A1 | Propolis extract with improved water-solubility | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1998-09-30 | — | — | EP | claimed |
| EP-0622068-B1 | Hair restorer | HAYASHIBARA BIOCHEM LAB (JP) | 1998-07-29 | — | — | EP | claimed |
| US-5710179-A | METAL 3-(4-HYDROXY-3,5-BIS(3-METHYL-2-BUTENYL)PHENYL)-2-PROPIONATE | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1998-01-20 | — | — | US | claimed |
| EP-0800826-A2 | Apoptosis-controlling agent | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1997-10-15 | — | — | EP | claimed |
| US-5556866-A | TREATMENT AND PREVENTION OF ALOPECIA | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1996-09-17 | — | — | US | claimed |
| EP-0622068-A2 | Hair restorer | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1994-11-02 | — | — | EP | claimed |
| JP-7330596-A | — | — | None | — | — | JP | disclosed |
| JP-9328425-A | — | — | None | — | — | JP | disclosed |
| EP-0622068-A2 | Hair restorer | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1994-11-02 | — | — | EP | disclosed |
| EP-0622068-A2 | Hair restorer | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 1994-11-02 | — | — | EP | disclosed |
| JP-H06256177-A | ANTIMICROBIAL COMPOSITION AND METHOD FOR PROVIDING ANTIMICROBIAL PROPERTY | HAYASHIBARA BIOCHEM LAB INC | 1994-09-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065229-A1 | Phenol derivatives, process for preparation of the same and use thereof | ACR, SHARPIN, AGPS | AKR1C3 192/4885AKR1B10 851/4885AKR1B1 1008/4885 |
| US-10314918-B2 | Jasmonate derivatives and compositions thereof | TRAF6, RELA, NFKBIA | AKR1C3 3082/4885AKR1B10 2758/4885AKR1B1 1954/4885 |
| US-20040126437-A1 | Typing natural products | ACHE, BCHE, HLA-C | AKR1C3 429/4885AKR1B10 807/4885AKR1B1 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.